CBD Bioavailability


When using CBD products, you may have noticed the word "bioavailability" in the context of effectiveness. If you haven't figured it out yet, we're here to help. As the range of CBD-fortified products grows wider, people are looking to get a better route and more benefits from natural remedies, so the question is bioavailability levels.

In this article, you will learn the bioavailability of CBD and how the level of bioavailability affects CBD products' effectiveness for you.


Bioavailability Definition


Bioavailability is the level of absorption of any substance that enters the body. The higher the bioavailability level, the stronger the agent will affect the body, and more will be distributed. This term is widely used in pharmacology.


If we are talking specifically about CBD, how you consume CBD affects its absorption and distribution throughout the body.


Because different CBD products have different absorption levels and rates, understanding how quickly and to what extent our body assimilates CBD will allow us to most accurately choose the best type of CBD.


Knowing the absorption level, we can also predict the effectiveness of CBD products for us and choose the most appropriate way to consume CBD.


Different Ways to Consume CBD


How CBD products are used is very varied. They can be chewed, eaten, dropped under the tongue, vaporized, or applied to the skin.


However, the body absorbs CBD in various ways, so a lot depends on how the CBD is used. The method you choose affects how long it takes to absorb into the bloodstream and how much your body eventually absorbs CBD.


Each of the forms of CBD products has advantages and disadvantages. Here are several methods by which the human body can absorb and reap the benefits of CBD.


CBD Edibles Bioavailability


Let's face it, CBD gummies and sweets are the most delicious way to add some CBD to your daily routine.


In several studies, the most optimistic bioavailability score for Edible CBD was around 17-20%. For example, if you take 60 mg of CBD in a gummy, your body probably only absorbed about 12 milligrams, i.e., 20% of the total dosage.


Why is this happening?


Edibles' bioavailability concept includes gum and sweets, and capsules, all types that pass through the digestive system and enter the body.


Thus, before it can enter the bloodstream and circulate through the body, CBD must go through several stages, affecting the level of bioavailability.


However, it is helpful to understand that some of the CBD break down as it passes through the digestive system, and it takes longer to reach blood flow and circulate throughout the body.


Although CBD Edibles have a relatively low absorption rate, it is still a widespread consumption method. Just keep your bioavailability level in mind the next time you consume your daily dosage of CBD along with gummies or other delicious CBD products.


Sublingual CBD Bioavailability


CBD oils and oral drops are also one of the most popular uses.

This method involves using CBD sublingually - you put a few drops of the oil under your tongue for about 1-3 minutes before swallowing.


Sublingual ingestion may improve the bioavailability of CBD.


Why is this method more effective?


When CBD drops come into contact with the oral mucosa, it absorbs the epithelium at the bottom of the tongue. In this area, under the tongue, there is a high density of blood vessels.


As a result, the substance can quickly enter into the venous circulation through penetration and then go into the body's arterial circulation.


This method does not require the entire passage through the digestive system and liver, as is the case with edibles, and it allows CBD particles to enter the bloodstream more quickly.


There is one more condition worth noting. CBD is fat-soluble, so eating it with fats can help increase bioavailability. Therefore, in our CBD drops, we use MCT coconut oil, which may work very well with CBD and increase CBD bioavailability.


In the Perfect Mix article, you can read more about the benefits of mixing MCT oil with cannabis extract.


However, the bioavailability of CBD drops is less than, for example, CBD inhalation and vaping.


CBD Isolate Bioavailability


The CBD isolate is often used for addition to vaping liquids and cosmetic products.

CBD vaporization has a reasonably high bioavailability rate, which can be up to 40%. During vaporization, the lungs absorb CBD very quickly. After passing through the lungs, cannabidiol quickly enters the bloodstream and can circulate throughout the body—the reason why people use CBD vapes.


However, it is also essential to consider the exact temperature at which evaporation is effective. If you use too high temperatures for vaping, then CBD will become useless. As a guideline, the vaping temperature can be (10-30W).


Vaporization can be a quick method, but not for everyone, as not everyone is a vape proponent. Fortunately, there are many CBD-enriched foods, and everyone can find what they like.


CBD Topical Bioavailability


CBD is rapidly gaining ground in the beauty, personal care, and skincare sectors.


Many CBD applications include a pain reliever, rubbing and CBD patches to acne lotions, and even makeup.


Using CBD often comes with many other natural ingredients that can complement each other and may enhance your effects. These can be essential oils, extracts of other plants.


CBD does not enter your bloodstream with topical use. Instead, it is absorbed by the pores on the skin and transferred to the dermis. The bioavailability of CBD by topical application is relatively low, although there is undoubtedly a certain level of absorption sufficient for a particular skin area.


CBD Nasal Bioavailability


Another method of using CBD, with reasonably high bioavailability, is the nasal route of use.


CBD Nasal Spray is a rare method and may not be suitable for everyone.

With this method, the cannabinoids absorb by the nasal cavity tissues, which allows CBD to enter the bloodstream while maintaining up to 40% of its concentration, which in turn may exceed the effect you expect.


Is it possible to increase the bioavailability of CBD?


We mentioned above that the simplest way to increase the bioavailability of cannabinoids when taken orally is to mix them with lipid substrate. CBD may attach to pass through the digestive system more efficiently.


Fatty foods such as hummus, dark natural chocolate, avocado, and vegetable oils such as coconut, olive, and even hemp are used as healthy examples of this.


If we are talking about potentially increasing the bioavailability of the CBD isolate when vaping, then in this case, we can divide the dosage of the vape into small portions and consume in short breaths.


At the end of this section, we want to point out that when trying to increase your CBD's bioavailability, always keep in mind the optimal daily dosage. Do not exceed it, as it is unnecessary.



The bioavailability of CBD is the percentage of absorption of a substance through the bloodstream. The absorption rate is significant because foods that are incorrectly selected in terms of bioavailability may not provide you with the maximum benefit and fulfill your expectations.


Without considering bioavailability, only a tiny part of the desired ingredient or compound can be absorbed and available to the body. The main factors that determine the bioavailability of CBD are the type of CBD product you consume and the way you consume it.


Understanding the bioavailability of CBD allows consumers to decide what is important to them about a product. If they want a tasty and easy way to consume CBD, then gummies and candies are great options.


If speed and efficiency are essential to you, it is best to use a sublingual oil tinctures or CBD for vaporization.


To make sure you're getting the best CBD product - whether it's balms, pain relievers, oral drops - you should always choose a brand that has a proven track record of effectiveness and reputation, like PATCH ADAM.

Which only uses CBD from organically grown hemp and tiered testing in third-party laboratories guaranteeing premium quality CBD.




**Please note this Website may contain general information relating to various medical conditions and their treatment. Such information is provided for informational purposes only and is not meant to be a substitute for advice provided by a doctor or other qualified health care professional. You should not use the information contained herein for diagnosing a health or fitness problem or disease. Always consult with a doctor or other health care professional for medical advice or information about diagnosis and treatment.**

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